CAD/CAM guided surgery in implant dentistry can significantly improve the predictability of treatment outcomes. However inadequate understanding and usage of the CAD/CAM guided implant surgery system will result in catastrophic surgical and prosthetic complications due to the nature of the guided surgery system being a ‘Blind Surgery’. This presentation will review the limitation of currently available CAD/CAM systems and corresponding possible clinical complications, solutions, and prevention. The most updated surgical protocol of the NeoNavi Guide surgery and its related clinical data will be presented step by step surgical procedure demonstration and hands-on experience.